It's a horrible irony that just when you want to be looking your most fresh and dewy - your honeymoon - your skin has just had eight hours-plus of dehydration.
Scary stat time: the relative humidity in most air-conditioned buildings is between 40 and 70 per cent; on an aircraft, it's around 20 per cent.
Thankfully, we've found the antidote to cabin fever skin: Anne Semonin Extreme Comfort Cream. It's a super-rich day cream full of nourishing ingredients like macademia oil, milk protein and beeswax - but it won't leave you looking like you've just dunked your face in a giant tub of Vaseline.
We slathered this on for a recent flight to Las Vegas and arrived with skin that felt normal. In fact, better than normal.
Thanks to the protective barrier formed by the beeswax, it also doubles as a hand cream: and the 50ml pot won't get you in trouble at airport security.
Anne Semonin Extreme Comfort Cream; £68 for 50ml; www.liberty.co.uk