Cartagena's most luxurious and historic hotel is a 400-year-old, five-star converted monastery.
The guest book includes Shakira and Mel Gibson, and the hotel has a resident toucan (who shows up around the same time as your croissant).
On arrival, order the Santa Clara coconut lemonade - just like sorbet in a glass and even better with a shot of rum.
If you're splashing out, there are two über-suites to choose from: the Fernando Botero, filled with the Colombian artist's work; and the bright white Junior Suite. Both overlook the pool and are stocked with delicious Hermès and Sisley products.
Santa Clara is perfectly positioned (next to Colombian writer Gabriel García Márquez's house) to explore the historic town: take a horse-drawn carriage through the cobbled streets and spend afternoons sipping mojitos by the pool.
The signature restaurant, 1621, is the place to go for fine dining - think octopus carpaccio and risotto followed by Colombian chocolate and coffee.
WOW FACTOR: The Pearl of Bride spa treatment. It lasts four and a half hours and includes use of the hammam, a scrub, Cleopatra's Bath, full-body massage, facial and mani-pedi - all using pearl extracts.
FLIGHT TIME: 16 hours.
GO: Journey Latin America www.journeylatinamerica.co.uk offers five days at the Sofitel Legend Santa Clara from £1,410 per person, B&B. Includes flights to Cartagena via Bogotá and transfers.