Behind an unobtrusive door in a wall, in the medieval hamlet of Megalohori, lies the upscale yet laidback Vedema Resort.

Built in the style of a village, whitewashed buildings line cobbled courtyards dripping in bougainvillea, overlooking acres of vineyards and the glittering Aegean sea beyond. Staying at Vedema is like being at the beautiful home of super-chic friends. Chilled-out tunes float out over the swimming pool, and service is friendly and attentive without ever being intrusive. Sample a rare vintage from the well-stocked wine cellars, and savour local epicurean specialities: salads with the famous Santorini tomato, and fava, a hummus-like dip made from broadbeans.

Accommodation consists of individually designed apartments and villas. Cool, spacious interiors open onto sun-drenched balconies and terraces, where you can enjoy a chilled glass of one of the famed Santorini wines while taking in the views. An immense volcanic eruption 3,500 years ago formed what are now Santorini's trademarks - striking cliffs and dramatic coasts - and local legend states this was the catastrophe that led to the demise of the lost city of Atlantis. True or not, Santorini is bathed in history, and Vedema is a great base from which to explore the island. Venture out to explore the black beaches of Perivolos, or the hot springs of Thirasia.

WOW FACTOR Vinsanto, the fine-dining restaurant, atmospherically located in a candlelit 400-year-old winery.

FLIGHT TIME 4hrs from the UK

GO Luxury Holiday Collection offers seven nights from £1,399, B&B. Includes flights and transfers